Thursday, November 14, 2013

Tumor Paint: Changing the way surgeons view and fight cancer (CNN)

Tumor Paint: Changing the way surgeons fight cancer -

"Olson and his team were able to identify a small protein, or peptide, in the scorpion's venom and use it to produce Tumor Paint. They grew a brain tumor on a mouse's back and injected the "paint" into a tail vein; within an hour, the cancer was lighting up. Tumor Paint was 500 times more sensitive than an MRI, and it didn't just work for brain cancer but breast, skin, prostate and colon cancers."

Link to full article here.
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Wednesday, November 13, 2013

Dexamethasone a Potential Treatment for Cancer-Related Fatigue (JOCO)

Dexamethasone (Photo credit: Wikipedia)
Oncology Times: "Dexamethasone helps to reduce cancer-related fatigue in patients with advanced disease, according to a double-blind, randomized, placebo-controlled trial published in the Journal of Clinical Oncology(2013;31:3076-3082)."


"Prior research demonstrating the benefit of steroids in advanced cancer patients is limited, and there are no validated studies using fatigue as a primary outcome,” he said. The study he led (senior author was Eduardo Bruera, MD) used validated tools in a controlled setting that met National Cancer Institute and National Comprehensive Cancer Network criteria. Moreover, the study demonstrated that dexamethasone at 4 mg twice daily was effective in treating cancer-related fatigue for a period of two weeks."

Link to full article here.
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About Onco-PRN

Welcome and thanks for visiting Onco-P.R.N. - The oncology website with a focus on all things oncology pharmacy/pain/palliative care-related. It is intended to be an information resource for those pharmacist and relevant health care professionals involved in whatever fashion with cancer and palliative care. Stay tuned for the latest and greatest links and information with respect to: oncology medications, continuing education, pharmaceutical care initiatives, pain and symptom control, supportive care topics, and whatever else that might fit into the theme.

*Note: This website is not affiliated with Alberta Health Services (AHS) or CAPhO and the opinions expressed herewithin are that of the author(s).

Pharmacy History

"The earliest known compilation of medicinal substances was ARIANA the Sushruta Samhita, an Indian Ayurvedic treatise attributed to Sushruta in the 6th century BC. However, the earliest text as preserved dates to the 3rd or 4th century AD.
Many Sumerian (late 6th millennium BC - early 2nd millennium BC) cuneiform clay tablets record prescriptions for medicine.[3]

Ancient Egyptian pharmacological knowledge was recorded in various papyri such as the Ebers Papyrus of 1550 BC, and the Edwin Smith Papyrus of the 16th century BC.

The earliest known Chinese manual on materia medica is the Shennong Bencao Jing (The Divine Farmer's Herb-Root Classic), dating back to the 1st century AD. It was compiled during the Han dynasty and was attributed to the mythical Shennong. Earlier literature included lists of prescriptions for specific ailments, exemplified by a manuscript "Recipes for 52 Ailments", found in the Mawangdui tomb, sealed in 168 BC. Further details on Chinese pharmacy can be found in the Pharmacy in China article."

From Wikipedia:

Journal of Palliative Medicine - Table of Contents

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