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Tuesday, January 10, 2012

Tissue Drug Level May Hold Key to NSCLC Response - in Meeting Coverage, AACR-IASLC from MedPage Today

Medical News: Tissue Drug Level May Hold Key to NSCLC Response - in Meeting Coverage, AACR-IASLC from MedPage Today

Action Points

- This study was published as an abstract and presented at a conference. These data and conclusions should be considered to be preliminary until published in a peer-reviewed journal.

- In this study, tumor levels of platinum-based chemotherapy proved to be the best predictor of response in patients with advanced non-small cell lung cancer.

- Patients whose tumors had low platinum concentrations also had a shorter time to recurrence and worse progression-free survival (PFS) and overall survival.

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Pharmacy History

"The earliest known compilation of medicinal substances was ARIANA the Sushruta Samhita, an Indian Ayurvedic treatise attributed to Sushruta in the 6th century BC. However, the earliest text as preserved dates to the 3rd or 4th century AD.
Many Sumerian (late 6th millennium BC - early 2nd millennium BC) cuneiform clay tablets record prescriptions for medicine.[3]

Ancient Egyptian pharmacological knowledge was recorded in various papyri such as the Ebers Papyrus of 1550 BC, and the Edwin Smith Papyrus of the 16th century BC.

The earliest known Chinese manual on materia medica is the Shennong Bencao Jing (The Divine Farmer's Herb-Root Classic), dating back to the 1st century AD. It was compiled during the Han dynasty and was attributed to the mythical Shennong. Earlier literature included lists of prescriptions for specific ailments, exemplified by a manuscript "Recipes for 52 Ailments", found in the Mawangdui tomb, sealed in 168 BC. Further details on Chinese pharmacy can be found in the Pharmacy in China article."

From Wikipedia: http://en.wikipedia.org/wiki/Pharmacy#History_of_pharmacy

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