Thursday, July 14, 2011

The V Foundation For Cancer Care: Jimmy V's 1993 ESPY Speech

On March 4, 1993, Jim Valvano was awarded the inaugural Arthur Ashe Courage and Humanitarian Award at the first annual ESPY Awards. The preceding wass his acceptance speech.

Full transcript at The V Foundation's website:

About The V Foundation:

"Since 1993, The V Foundation has raised more than $100 million and awarded cancer research grants in 38 states and the District of Columbia. Researchers have developed their laboratories and taken their science from the labs to the clinics with the help of funds raised by The V Foundation.

The V Foundation started with the dream of Jim Valvano, the passionate and committed former NC State basketball coach and award-winning broadcaster, as he battled cancer. Wanting to see the battle through to victory, Valvano recruited friends and family to lead The V Foundation in his quest to eradicate the disease that ultimately claimed his life. With a dire need for early developmental, critical-stage grant support, the Foundation was formed to assist the brilliant young researchers that will eventually find cures for cancer.

A relatively young organization, The V Foundation has a strong presence in the scientific community that belies its youth."


Friday, July 8, 2011

Pain & Opiates 3D Animation


The Mechanisms of Musculoskeletal Pain


Pain Perception and the Human Brain


Central Nervous System Mechanisms of Pain Modulation


Phases of Nociceptive Pain


Thursday, July 7, 2011

FDA Okays Fentanyl Nasal Spray for Ca Pain - in Public Health & Policy, FDA General from MedPage Today

Medical News: FDA Okays Nasal Spray for Ca Pain - in Public Health & Policy, FDA General from MedPage Today

By Cole Petrochko, Associate Staff Writer, MedPage TodayPublished:

July 02, 2011 WASHINGTO -- The FDA has approved a nasal spray formulation of the drug fentanyl (Lazanda) to manage breakthrough pain in cancer patients ages 18 and older who are already using opioid therapy. The drug comes in 100 mcg- and 400 mcg-spray doses.

Drug efficacy was established in a double-blind study that found fentanyl nasal spray outperformed placebo at the primary endpoint of sum of pain intensity difference at 30 minutes.

The nasal spray formulation is not equivalent to other fentanyl products for breakthrough pain on a microgram-per-microgram basis. Healthcare professionals prescribing Lazanda should not convert from other fentanyl products. A dosage conversion guide is not available at this time.


Everolimus Trial Stopped for Benefit in Breast Cancer - in Oncology/Hematology, Breast Cancer from MedPage Today

Medical News: Everolimus Trial Stopped for Benefit in Breast Cancer - in Oncology/Hematology, Breast Cancer from MedPage Today


"A phase III trial of everolimus (Afinitor) in locally advanced or metastatic breast cancer has been halted after an interim analysis indicated that the study's primary endpoint -- a significant difference in progression-free survival relative to a control therapy after six weeks -- was met, the drug's manufacturer said.

According to Novartis, the combination of everolimus and exemestane (Aromasin) was more effective than the latter drug and placebo in preventing tumor growth in women with estrogen receptor-positive, HER2-negative breast cancer that did not respond to other aromatase inhibitors.

The international trial, BOLERO-2, was testing everolimus at 10 mg/day orally plus 25 mg/day of oral exemestane. It included more than 700 patients randomized 2:1 to the combination versus the control regimen.

Novartis did not indicate the degree of improvement in progression-free survival with the combination. It promised that full results would be presented at "an upcoming medical conference" and that it would file marketing applications worldwide by the end of this year."

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About Onco-PRN

Welcome and thanks for visiting Onco-P.R.N. - The oncology website with a focus on all things oncology pharmacy/pain/palliative care-related. It is intended to be an information resource for those pharmacist and relevant health care professionals involved in whatever fashion with cancer and palliative care. Stay tuned for the latest and greatest links and information with respect to: oncology medications, continuing education, pharmaceutical care initiatives, pain and symptom control, supportive care topics, and whatever else that might fit into the theme.

*Note: This website is not affiliated with Alberta Health Services (AHS) or CAPhO and the opinions expressed herewithin are that of the author(s).

Pharmacy History

"The earliest known compilation of medicinal substances was ARIANA the Sushruta Samhita, an Indian Ayurvedic treatise attributed to Sushruta in the 6th century BC. However, the earliest text as preserved dates to the 3rd or 4th century AD.
Many Sumerian (late 6th millennium BC - early 2nd millennium BC) cuneiform clay tablets record prescriptions for medicine.[3]

Ancient Egyptian pharmacological knowledge was recorded in various papyri such as the Ebers Papyrus of 1550 BC, and the Edwin Smith Papyrus of the 16th century BC.

The earliest known Chinese manual on materia medica is the Shennong Bencao Jing (The Divine Farmer's Herb-Root Classic), dating back to the 1st century AD. It was compiled during the Han dynasty and was attributed to the mythical Shennong. Earlier literature included lists of prescriptions for specific ailments, exemplified by a manuscript "Recipes for 52 Ailments", found in the Mawangdui tomb, sealed in 168 BC. Further details on Chinese pharmacy can be found in the Pharmacy in China article."

From Wikipedia:

Journal of Palliative Medicine - Table of Contents

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