ShareThis

Thursday, August 23, 2012

Pain Management - Oncology News Article | Onabotulinumtoxina for treatment of focal cancer pain after surgery and/or radiation |4134185

Pain Management - Oncology News Article | Onabotulinumtoxina for treatment of focal cancer pain after surgery and/or radiation |4134185

Excerpt:
Pain Medicine, 07/17/2012 Clinical Article

Mittal S et al. – Local treatment with onabotulinumtoxinA can significantly reduce pain and improve quality of life in cancer patients suffering from pain in the area of surgery and radiation and was well tolerated in cancer patients.


Methods

Authors studied the effect of onabotulinumtoxinA in seven cancer patients who suffered from severe focal pain (visual analog scale >5) at the site of local surgery or radiotherapy or both.

OnabotulinumtoxinA (20–100 units) was injected into the focal pain areas (skin or muscle or both).

Five of seven patients were followed beyond 1 year (1.5–5 years) with repeat treatment.


Results

All seven patients reported a significant improvement in pain (mean drop in visual analog scale score of 5.1).

They described their response on the patient global assessment as satisfactory (two patients) or very satisfactory (five patients).

Six of seven patients found the pain relief associated with significant improvement in quality of life.

One patient developed weakness of jaw muscles after bilateral masseter injection that was not observed during second injection (reduced dose).

Improvements with treatment persisted with repeat injections during long–term follow–up (five patients). "

0 comments:

Related Posts Plugin for WordPress, Blogger...

About Onco-PRN

Welcome and thanks for visiting Onco-P.R.N. - The oncology website with a focus on all things oncology pharmacy/pain/palliative care-related. It is intended to be an information resource for those pharmacist and relevant health care professionals involved in whatever fashion with cancer and palliative care. Stay tuned for the latest and greatest links and information with respect to: oncology medications, continuing education, pharmaceutical care initiatives, pain and symptom control, supportive care topics, and whatever else that might fit into the theme.

*Note: This website is not affiliated with Alberta Health Services (AHS) or CAPhO and the opinions expressed herewithin are that of the author(s).

Pharmacy History

"The earliest known compilation of medicinal substances was ARIANA the Sushruta Samhita, an Indian Ayurvedic treatise attributed to Sushruta in the 6th century BC. However, the earliest text as preserved dates to the 3rd or 4th century AD.
Many Sumerian (late 6th millennium BC - early 2nd millennium BC) cuneiform clay tablets record prescriptions for medicine.[3]

Ancient Egyptian pharmacological knowledge was recorded in various papyri such as the Ebers Papyrus of 1550 BC, and the Edwin Smith Papyrus of the 16th century BC.

The earliest known Chinese manual on materia medica is the Shennong Bencao Jing (The Divine Farmer's Herb-Root Classic), dating back to the 1st century AD. It was compiled during the Han dynasty and was attributed to the mythical Shennong. Earlier literature included lists of prescriptions for specific ailments, exemplified by a manuscript "Recipes for 52 Ailments", found in the Mawangdui tomb, sealed in 168 BC. Further details on Chinese pharmacy can be found in the Pharmacy in China article."

From Wikipedia: http://en.wikipedia.org/wiki/Pharmacy#History_of_pharmacy

Journal of Palliative Medicine - Table of Contents

  © Blogger templates Newspaper III by Ourblogtemplates.com 2008

Back to TOP