Ketamine mouthwash for mucositis pain
Journal of Palliative Medicine, 09/01/09
Ryan AJ et al. – Ketamine swish and expectorate may be a viable treatment option in refractory mucositis pain.
A retrospective chart audit was preformed on eight patients who received ketamine mouthwash (20mg/5mL) for refractory mucositis pain.
All eight patients had mucositis pain refractory to a mucositis mixture (lidocaine, magnesium/aluminum hydroxide, and diphenhydramine) and opioids.
An improvement in mucositis pain was seen in over half (5/8) of the patients.
Four of eight patients had adverse effects that could have been associated with the ketamine mouthwash; all side effects were transient and subsided when the ketamine mouthwash was stopped.
The following articles discuss management of oral mucositis:
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Tuesday, September 15, 2009